Often times, system administrators do not want to store the vault data on the root drive of their server. Sometimes, the drive just isn't big enough or some other reason. Setting the storage location for the file store and database of a vault can be changed to any location on the network.
To change this location for an existing vault, ADMS Console 2008 and log in as an administrator. Right click on the vault that you want to move the database for and select Detach. This will remove the vault from the console but will not change any of the database or filestore files. Now, simply move the files to the location you want. The database files, by default, are located in C:\Program Files\Microsoft SQL Server\MSSQL$AUTODESKVAULT\Data. Simpy move the files that start with the vaults name that you detached to the desired location. You can also move the filestore as well which by default is located here: C:\Documents and Settings\All Users\Application Data\Autodesk\VaultServer\FileStore.
Now that they are moved, you simply reattach them to the console. In the ADMS Console, right click on Vaults and select Attach. You'll be given a dialog box that will guide you through selecting the files and locations and that's all there is to it.